ABSTRACT Productive replication of herpes simplex virus (HSV) relies upon a well-ordered transcriptional cascade flowing from immediate-early (IE) to early (E) to late (L) gene products.While several virus-encoded transcriptional activators are involved in this process, IE and E gene promoters also contain multiple binding sites for the ubiquitousl
Energy consumption has become an essential factor in designing modern computer system architecture.Because of physical limits, the termination of Moore’s law and Dennard’s scaling has forced the computer design community to investigate new approaches to meet the requirements for computing resources.Approximate Horse Summer Sheets comp
Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder characterized by skin rash (poikiloderma), skeletal dysplasia, small stature, juvenile cataracts, sparse or absent hair, and predisposition to specific malignancies such as osteosarcoma and hematological neoplasms.RTS is caused by germ-line mutations in RECQL4, a RecQ helicase f
During clathrin-mediated endocytosis in yeast cells, a small patch of flat membrane is deformed into a tubular shape.It is generally believed that the tubulation is powered by actin polymerization.However, studies based on quantitative measurement of the actin molecules suggest that they are not sufficient to produce the forces to overcome the high